Lunedì, 22 Ottobre 2018

'Bad' white fat can be turned into brown fat furnace


ß ßßRome, February 22 - An Italian group of scientists
have for the first time transformed human white-fat tissue - the
fat people accumulate on bellies and fight to get rid of - into
a brown-fat tissue that burns off the white variety,ßand has
been published in the magazine BBA-Molecular and Cell Biology of
Brown fat - more formally known as brown adipose tissue -
acts as a furnace for mammal bodies, using white fat as fuel to
produce heat when the body gets cold.
Years of research have demonstrated that the transformation
from white to brown fat can occur in animal tissue, but a
research team led by Saverio Cinti at the University of Ancona
directly observed the transformation for the first time in
humans - and demonstrated that the process can be directly
Researchers saw the switch from white to brown adipose
tissue in patients with a rare, benign tumor called
pheochromocytoma, which affects the adrenal gland.
The discovery opens a path of research into substances that
could directly stimulate identity change in fat.
"We have demonstrated that what has been observed in mice
happens also in humans and that it is possible to induce the
transformation," said Cinti.
Cinti added that the discovery opens the path to research
new molecules that could have pharmaceutical applications.

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